Kazuo Kitagawa Selected Research

Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)

10/2013	Functional deterioration of endothelial nitric oxide synthase after focal cerebral ischemia.
9/2011	Cilostazol, not aspirin, reduces ischemic brain injury via endothelial protection in spontaneously hypertensive rats.
10/2010	An angiotensin II type 1 receptor blocker can preserve endothelial function and attenuate brain ischemic damage in spontaneously hypertensive rats.
8/2007	Rho-kinase activation in endothelial cells contributes to expansion of infarction after focal cerebral ischemia.

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Kazuo Kitagawa Research Topics

Disease

53	Stroke (Strokes) 02/2024 - 09/2002
45	Ischemic Stroke 12/2023 - 04/2005
24	Ischemia 12/2016 - 01/2002
22	Infarction (Infarctions) 11/2022 - 02/2004
17	Atherosclerosis 06/2023 - 02/2002
15	Brain Ischemia (Cerebral Ischemia) 05/2023 - 04/2002
15	Hypertension (High Blood Pressure) 01/2021 - 02/2003
10	Atrial Fibrillation 04/2023 - 05/2004
10	Hemorrhage 01/2023 - 01/2014
9	Carotid Artery Diseases 10/2014 - 06/2002
8	Cerebral Infarction 08/2021 - 06/2002
7	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 11/2022 - 08/2004
7	Myocardial Infarction 01/2020 - 09/2009
5	Acute Coronary Syndrome 01/2023 - 01/2014
5	Transient Ischemic Attack 11/2022 - 08/2005
5	Embolic Stroke 09/2021 - 01/2013
5	Lacunar Stroke 05/2020 - 06/2002
5	Embolism (Embolus) 12/2019 - 09/2005
5	Type 2 Diabetes Mellitus (MODY) 01/2019 - 12/2009
5	Dementia (Dementias) 11/2018 - 01/2010
5	Inflammation (Inflammations) 10/2017 - 05/2003
4	Neoplasms (Cancer) 03/2024 - 01/2013
4	Pathologic Constriction (Stenosis) 01/2023 - 05/2003
4	Parkinson Disease (Parkinson's Disease) 01/2021 - 06/2015
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2020 - 04/2006
4	Coronary Artery Disease (Coronary Atherosclerosis) 01/2018 - 01/2014
4	Thrombosis (Thrombus) 01/2013 - 09/2005
3	Dyslipidemias (Dyslipidemia) 07/2022 - 01/2014
3	Intracranial Hemorrhages (Intracranial Hemorrhage) 09/2021 - 09/2015
3	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 12/2020 - 08/2019
3	Cerebrovascular Disorders (Cerebrovascular Occlusion) 11/2018 - 09/2004
3	Diabetes Mellitus 04/2018 - 01/2017
3	Hyperlipidemias (Hyperlipidemia) 04/2018 - 02/2014
3	Cerebral Small Vessel Diseases 01/2016 - 04/2005
3	Hemorrhagic Stroke 09/2015 - 01/2011
2	Colorectal Neoplasms (Colorectal Cancer) 03/2024 - 05/2023
2	Intracranial Aneurysm (Cerebral Aneurysm) 07/2023 - 04/2023
2	Cardiomyopathies (Cardiomyopathy) 04/2023 - 09/2021
2	Melanoma (Melanoma, Malignant) 01/2023 - 01/2011
2	Edema (Dropsy) 12/2022 - 12/2009
2	Hypertriglyceridemia 07/2022 - 01/2022
2	Neuromyelitis Optica (Devic's Disease) 01/2021 - 01/2018
2	Myasthenia Gravis 01/2020 - 04/2019
2	Hypercholesterolemia 05/2019 - 01/2018
2	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2019 - 01/2018
2	Fabry Disease (Fabry's Disease) 01/2019 - 01/2019
2	Brain Infarction 01/2019 - 04/2005

Drug/Important Bio-Agent (IBA)

19	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 01/2022 - 11/2007
15	Clopidogrel (Plavix)FDA Link 12/2023 - 11/2009
12	Pravastatin (Pravachol)FDA LinkGeneric 06/2020 - 11/2007
12	C-Reactive ProteinIBA 05/2019 - 03/2004
9	Proteins (Proteins, Gene)FDA Link 05/2023 - 01/2002
9	Prasugrel Hydrochloride FDA Link 02/2021 - 01/2014
8	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 01/2023 - 05/2004
8	LDL CholesterolIBA 01/2022 - 01/2018
7	Warfarin (Coumadin)FDA LinkGeneric 09/2021 - 09/2005
7	AnticoagulantsIBA 09/2021 - 09/2005
6	Interleukin-6 (Interleukin 6)IBA 01/2023 - 03/2004
6	Glucose (Dextrose)FDA LinkGeneric 11/2022 - 02/2007
6	Glutamic Acid (Glutamate)FDA Link 12/2020 - 04/2002
6	Oxygen (Dioxygen)IBA 12/2016 - 09/2002
6	Apolipoproteins E (ApoE)IBA 01/2016 - 02/2002
5	Cilostazol (Pletal)FDA LinkGeneric 01/2023 - 09/2011
5	omega-Chloroacetophenone (Mace)IBA 01/2023 - 01/2014
5	EnzymesIBA 07/2022 - 10/2003
5	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 09/2021 - 09/2005
5	Antihypertensive Agents (Antihypertensives)IBA 01/2011 - 01/2005
4	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 10/2013 - 08/2007
3	HomocysteineIBA 09/2023 - 06/2002
3	2'- deoxythymidylyl- (3'- 5')- 2'- deoxyadenosine (d(AT))IBA 07/2023 - 01/2023
3	Immunoglobulin G (IgG)IBA 01/2023 - 01/2018
3	Triglycerides (Triacylglycerol)IBA 11/2022 - 01/2022
3	salicylhydroxamic acid (SHAM)IBA 11/2022 - 03/2002
3	LDL Lipoproteins (beta Lipoproteins)IBA 05/2020 - 01/2018
3	CholesterolIBA 01/2020 - 02/2014
3	Tissue Plasminogen Activator (Alteplase)FDA Link 01/2020 - 05/2012
3	InterleukinsIBA 01/2018 - 10/2012
3	Neuroprotective AgentsIBA 12/2016 - 04/2002
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 12/2014 - 08/2010
3	Pioglitazone (Actos)FDA Link 01/2014 - 12/2009
3	Interleukin-18 (Interleukin 18)IBA 02/2013 - 07/2005
3	Bromodeoxyuridine (BrdU)IBA 05/2007 - 03/2002
3	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 03/2005 - 02/2002
3	ApolipoproteinsIBA 11/2002 - 02/2002
2	Levetiracetam (Keppra)FDA LinkGeneric 07/2023 - 01/2022
2	danaparoid (Orgaran)FDA Link 06/2023 - 12/2015
2	Interleukin-10 (Interleukin 10)IBA 01/2023 - 01/2018
2	Immune Checkpoint InhibitorsIBA 01/2023 - 04/2019
2	Interleukin-2 Receptors (IL 2 Receptor)IBA 01/2023 - 01/2018
2	SteroidsIBA 01/2021 - 02/2019
2	HDL CholesterolIBA 01/2020 - 04/2018
2	edoxabanIBA 12/2019 - 09/2015
2	oxidized low density lipoproteinIBA 05/2019 - 01/2018
2	Cytochrome P-450 CYP2C19IBA 01/2019 - 01/2016

Therapy/Procedure

33	Therapeutics 07/2023 - 09/2004
7	Secondary Prevention 02/2024 - 09/2009
4	Percutaneous Coronary Intervention 01/2016 - 01/2014
2	Stents 07/2023 - 04/2023
2	Catheter Ablation 04/2023 - 12/2019
2	Enzyme Replacement Therapy 01/2019 - 01/2019